Loss of wobble uridine modification in tRNA anticodons interferes with TOR pathway signaling

Previous work in yeast has suggested that modification of tRNAs, in particular uridine bases in the anticodon wobble position (U34), is linked to TOR (target of rapamycin) signaling. Hence, U34 modification mutants were found to be hypersensitive to TOR inhibition by rapamycin. To study whether this...

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Detalles Bibliográficos
Autores principales: Scheidt, Viktor, Jüdes, André, Bär, Christian, Klassen, Roland, Schaffrath, Raffael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2014
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349137/
https://www.ncbi.nlm.nih.gov/pubmed/28357221
http://dx.doi.org/10.15698/mic2014.12.179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349137/
https://www.ncbi.nlm.nih.gov/pubmed/28357221
http://dx.doi.org/10.15698/mic2014.12.179

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