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Exogenous addition of histidine reduces copper availability in the yeast Saccharomyces cerevisiae
The basic amino acid histidine inhibited yeast cell growth more severely than lysine and arginine. Overexpression of CTR1, which encodes a high-affinity copper transporter on the plasma membrane, or addition of copper to the medium alleviated this cytotoxicity. However, the intracellular level of co...
Autores principales: | Watanabe, Daisuke, Kikushima, Rie, Aitoku, Miho, Nishimura, Akira, Ohtsu, Iwao, Nasuno, Ryo, Takagi, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349156/ https://www.ncbi.nlm.nih.gov/pubmed/28357248 http://dx.doi.org/10.15698/mic2014.07.154 |
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