Cargando…
Toxoplasma gondii inhibits cytochrome c-induced caspase activation in its host cell by interference with holo-apoptosome assembly
Inhibition of programmed cell death pathways of mammalian cells often facilitates the sustained survival of intracellular microorganisms. The apicomplexan parasite Toxoplasma gondii is a master regulator of host cell apoptotic pathways. Here, we have characterized a novel anti-apoptotic activity of...
Autores principales: | Graumann, Kristin, Schaumburg, Frieder, Reubold, Thomas F., Hippe, Diana, Eschenburg, Susanne, Lüder, Carsten G. K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349237/ https://www.ncbi.nlm.nih.gov/pubmed/28357287 http://dx.doi.org/10.15698/mic2015.05.201 |
Ejemplares similares
-
The Apoptosome Pathway to Caspase Activation in Primary Human Neutrophils Exhibits Dramatically Reduced Requirements for Cytochrome c
por: Murphy, Brona M., et al.
Publicado: (2003) -
Long-Term Impact of Toxoplasma gondii Infection on Human Monocytes
por: Ehmen, Hauke G., et al.
Publicado: (2019) -
Structure of the apoptosome: mechanistic insights into activation of an initiator caspase from Drosophila
por: Pang, Yuxuan, et al.
Publicado: (2015) -
A Short Caspase-3 Isoform Inhibits Chemotherapy-Induced Apoptosis by Blocking Apoptosome Assembly
por: Végran, Frédérique, et al.
Publicado: (2011) -
Epigenetic Control of IFN-γ Host Responses During Infection With Toxoplasma gondii
por: Nast, Roswitha, et al.
Publicado: (2020)