Deciphering the interplay between cysteine synthase and thiol cascade proteins in modulating Amphotericin B resistance and survival of Leishmania donovani under oxidative stress

Leishmania donovani is the causative organism of the neglected human disease known as visceral leishmaniasis which is often fatal, if left untreated. The cysteine biosynthesis pathway of Leishmania may serve as a potential drug target because it is different from human host and regulates downstream...

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Detalles Bibliográficos
Autores principales: Singh, Kuljit, Ali, Vahab, Pratap Singh, Krishn, Gupta, Parool, Suman, Shashi S., Ghosh, Ayan K., Bimal, Sanjiva, Pandey, Krishna, Das, Pradeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349463/
https://www.ncbi.nlm.nih.gov/pubmed/28288415
http://dx.doi.org/10.1016/j.redox.2017.03.004

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