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CO-releasing molecules CORM2 attenuates angiotensin II-induced human aortic smooth muscle cell migration through inhibition of ROS/IL-6 generation and matrix metalloproteinases-9 expression

Ang II has been involved in the pathogenesis of cardiovascular diseases, and matrix metalloproteinase-9 (MMP-9) induced migration of human aortic smooth muscle cells (HASMCs) is the most common and basic pathological feature. Carbon monoxide (CO), a byproduct of heme breakdown by heme oxygenase, exe...

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Detalles Bibliográficos
Autores principales: Tsai, Ming-Horng, Lee, Chiang-Wen, Hsu, Lee-Fen, Li, Shu-Yu, Chiang, Yao-Chang, Lee, Ming-Hsueh, Chen, Chun-Han, Liang, Hwey-Fang, How, Jia-Mei, Chang, Pey-Jium, Wu, Ching-Mei, Lee, I-Ta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349464/
https://www.ncbi.nlm.nih.gov/pubmed/28292711
http://dx.doi.org/10.1016/j.redox.2017.02.019