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Structural Basis of Eco1-Mediated Cohesin Acetylation

Sister-chromatid cohesion is established by Eco1-mediated acetylation on two conserved tandem lysines in the cohesin Smc3 subunit. However, the molecular basis of Eco1 substrate recognition and acetylation in cohesion is not fully understood. Here, we discover and rationalize the substrate specifici...

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Detalles Bibliográficos
Autores principales:	Chao, William C. H., Wade, Benjamin O., Bouchoux, Céline, Jones, Andrew W., Purkiss, Andrew G., Federico, Stefania, O’Reilly, Nicola, Snijders, Ambrosius P., Uhlmann, Frank, Singleton, Martin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349539/ https://www.ncbi.nlm.nih.gov/pubmed/28290497 http://dx.doi.org/10.1038/srep44313

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