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TIR/BB-loop mimetic AS-1 attenuates cardiac ischemia/reperfusion injury via a caveolae and caveolin-3-dependent mechanism

AS-1, the TIR/BB loop mimetic, plays a protective role in cardiac ischemia/reperfusion (I/R) but the molecular mechanism remains unclear. The muscle specific caveolin3 (Cav-3) and the caveolae have been found to be critical for cardioprotection. This study aimed to evaluate our hypothesis that caveo...

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Detalles Bibliográficos
Autores principales:	Hu, Yuanping, Zhang, Meiling, Shen, Xin, Dai, Guoliang, Ren, Danyang, Que, Linli, Ha, Tuanzhu, Li, Chuanfu, Xu, Yong, Ju, Wenzheng, Li, Yuehua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349563/ https://www.ncbi.nlm.nih.gov/pubmed/28291255 http://dx.doi.org/10.1038/srep44638

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