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Epithelial LTβR signaling controls the population size of the progenitors of medullary thymic epithelial cells in neonatal mice
The establishment of T cell central tolerance critically relies on the development and maintenance of the medullary thymic epithelial cells (mTECs). Disrupted signaling of lymphotoxin beta receptor (LTβR) results in dramatically reduced mTEC population. However, whether LTβR directly or indirectly c...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349570/ https://www.ncbi.nlm.nih.gov/pubmed/28290551 http://dx.doi.org/10.1038/srep44481 |