Activated hepatic stellate cells impair NK cell anti-fibrosis capacity through a TGF-β-dependent emperipolesis in HBV cirrhotic patients

Natural killer (NK) cells can induce liver fibrosis remission by killing hepatic stellate cells (HSCs) and producing interferon (IFN)-γ in a mouse model; however, their anti-fibrotic immune-characteristics and regulatory mechanisms by HSCs remain to be determined, especially in livers from HBV-infec...

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Detalles Bibliográficos
Autores principales: Shi, Jijing, Zhao, Juanjuan, Zhang, Xin, Cheng, Yongqian, Hu, Jinhua, Li, Yuanyuan, Zhao, Xin, Shang, Qinghua, Sun, Yanling, Tu, Bo, Shi, Lei, Gao, Bin, Wang, Fu-Sheng, Zhang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349579/
https://www.ncbi.nlm.nih.gov/pubmed/28291251
http://dx.doi.org/10.1038/srep44544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349579/
https://www.ncbi.nlm.nih.gov/pubmed/28291251
http://dx.doi.org/10.1038/srep44544

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