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Identification of Elongated Primary Cilia with Impaired Mechanotransduction in Idiopathic Scoliosis Patients
The primary cilium is an outward projecting antenna-like organelle with an important role in bone mechanotransduction. The capacity to sense mechanical stimuli can affect important cellular and molecular aspects of bone tissue. Idiopathic scoliosis (IS) is a complex pediatric disease of unknown caus...
Autores principales: | Oliazadeh, Niaz, Gorman, Kristen F., Eveleigh, Robert, Bourque, Guillaume, Moreau, Alain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349607/ https://www.ncbi.nlm.nih.gov/pubmed/28290481 http://dx.doi.org/10.1038/srep44260 |
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