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Liver-specific deletion of the Plpp3 gene alters plasma lipid composition and worsens atherosclerosis in apoE(−/−) mice

The PLPP3 gene encodes for a ubiquitous enzyme that dephosphorylates several lipid substrates. Genome-wide association studies identified PLPP3 as a gene that plays a role in coronary artery disease susceptibility. The aim of the study was to investigate the effect of Plpp3 deletion on atheroscleros...

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Detalles Bibliográficos
Autores principales:	Busnelli, Marco, Manzini, Stefano, Hilvo, Mika, Parolini, Cinzia, Ganzetti, Giulia S., Dellera, Federica, Ekroos, Kim, Jänis, Minna, Escalante-Alcalde, Diana, Sirtori, Cesare R., Laaksonen, Reijo, Chiesa, Giulia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349609/ https://www.ncbi.nlm.nih.gov/pubmed/28291223 http://dx.doi.org/10.1038/srep44503

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