Cargando…
Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery
In a Perspective, David Bennett makes a case for neural reserve to be considered as a therapeutic endpoint in clinical trials for dementia.
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349649/ https://www.ncbi.nlm.nih.gov/pubmed/28291788 http://dx.doi.org/10.1371/journal.pmed.1002256 |
_version_ | 1782514510283669504 |
---|---|
author | Bennett, David A. |
author_facet | Bennett, David A. |
author_sort | Bennett, David A. |
collection | PubMed |
description | In a Perspective, David Bennett makes a case for neural reserve to be considered as a therapeutic endpoint in clinical trials for dementia. |
format | Online Article Text |
id | pubmed-5349649 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-53496492017-04-06 Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery Bennett, David A. PLoS Med Perspective In a Perspective, David Bennett makes a case for neural reserve to be considered as a therapeutic endpoint in clinical trials for dementia. Public Library of Science 2017-03-14 /pmc/articles/PMC5349649/ /pubmed/28291788 http://dx.doi.org/10.1371/journal.pmed.1002256 Text en © 2017 David A. Bennett http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Perspective Bennett, David A. Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery |
title | Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery |
title_full | Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery |
title_fullStr | Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery |
title_full_unstemmed | Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery |
title_short | Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery |
title_sort | mixed pathologies and neural reserve: implications of complexity for alzheimer disease drug discovery |
topic | Perspective |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349649/ https://www.ncbi.nlm.nih.gov/pubmed/28291788 http://dx.doi.org/10.1371/journal.pmed.1002256 |
work_keys_str_mv | AT bennettdavida mixedpathologiesandneuralreserveimplicationsofcomplexityforalzheimerdiseasedrugdiscovery |