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Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings
This study aimed to explore the utility of arterial spin labeling perfusion-weighted imaging (ASL-PWI) in patients with suspected seizures in acute settings. A total of 164 patients who underwent ASL-PWI for suspected seizures in acute settings (with final diagnoses of seizure [n = 129], poststroke...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349669/ https://www.ncbi.nlm.nih.gov/pubmed/28291816 http://dx.doi.org/10.1371/journal.pone.0173538 |
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author | Yoo, Roh-Eul Yun, Tae Jin Yoon, Byung-Woo Lee, Sang Kun Lee, Soon-Tae Kang, Koung Mi Choi, Seung Hong Kim, Ji-hoon Sohn, Chul-Ho Park, Sun-Won Han, Moon Hee |
author_facet | Yoo, Roh-Eul Yun, Tae Jin Yoon, Byung-Woo Lee, Sang Kun Lee, Soon-Tae Kang, Koung Mi Choi, Seung Hong Kim, Ji-hoon Sohn, Chul-Ho Park, Sun-Won Han, Moon Hee |
author_sort | Yoo, Roh-Eul |
collection | PubMed |
description | This study aimed to explore the utility of arterial spin labeling perfusion-weighted imaging (ASL-PWI) in patients with suspected seizures in acute settings. A total of 164 patients who underwent ASL-PWI for suspected seizures in acute settings (with final diagnoses of seizure [n = 129], poststroke seizure [n = 18], and seizure mimickers [n = 17]), were included in this retrospective study. Perfusion abnormality was analyzed for: (1) pattern, (2) multifocality, and (3) atypical distribution against vascular territories. Perfusion abnormality was detected in 39% (50/129) of the seizure patients, most (94%, 47/50) being the hyperperfusion pattern. Of the patients with perfusion abnormality, multifocality or hemispheric involvement and atypical distribution against vascular territory were revealed in 46% (23/50) and 98% (49/50), respectively. In addition, seizures showed characteristic features including hyperperfusion (with or without non-territorial distribution) on ASL-PWI, thus differentiating them from poststroke seizures or seizure mimickers. In patients in whom seizure focus could be localized on both EEG and ASL-PWI, the concordance rate was 77%. The present study demonstrates that ASL-PWI can provide information regarding cerebral perfusion status in patients with seizures in acute settings and has the potential to be used as a non-invasive imaging tool to identify the cerebral perfusion in patients with seizures. |
format | Online Article Text |
id | pubmed-5349669 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-53496692017-04-06 Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings Yoo, Roh-Eul Yun, Tae Jin Yoon, Byung-Woo Lee, Sang Kun Lee, Soon-Tae Kang, Koung Mi Choi, Seung Hong Kim, Ji-hoon Sohn, Chul-Ho Park, Sun-Won Han, Moon Hee PLoS One Research Article This study aimed to explore the utility of arterial spin labeling perfusion-weighted imaging (ASL-PWI) in patients with suspected seizures in acute settings. A total of 164 patients who underwent ASL-PWI for suspected seizures in acute settings (with final diagnoses of seizure [n = 129], poststroke seizure [n = 18], and seizure mimickers [n = 17]), were included in this retrospective study. Perfusion abnormality was analyzed for: (1) pattern, (2) multifocality, and (3) atypical distribution against vascular territories. Perfusion abnormality was detected in 39% (50/129) of the seizure patients, most (94%, 47/50) being the hyperperfusion pattern. Of the patients with perfusion abnormality, multifocality or hemispheric involvement and atypical distribution against vascular territory were revealed in 46% (23/50) and 98% (49/50), respectively. In addition, seizures showed characteristic features including hyperperfusion (with or without non-territorial distribution) on ASL-PWI, thus differentiating them from poststroke seizures or seizure mimickers. In patients in whom seizure focus could be localized on both EEG and ASL-PWI, the concordance rate was 77%. The present study demonstrates that ASL-PWI can provide information regarding cerebral perfusion status in patients with seizures in acute settings and has the potential to be used as a non-invasive imaging tool to identify the cerebral perfusion in patients with seizures. Public Library of Science 2017-03-14 /pmc/articles/PMC5349669/ /pubmed/28291816 http://dx.doi.org/10.1371/journal.pone.0173538 Text en © 2017 Yoo et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Yoo, Roh-Eul Yun, Tae Jin Yoon, Byung-Woo Lee, Sang Kun Lee, Soon-Tae Kang, Koung Mi Choi, Seung Hong Kim, Ji-hoon Sohn, Chul-Ho Park, Sun-Won Han, Moon Hee Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings |
title | Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings |
title_full | Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings |
title_fullStr | Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings |
title_full_unstemmed | Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings |
title_short | Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings |
title_sort | identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349669/ https://www.ncbi.nlm.nih.gov/pubmed/28291816 http://dx.doi.org/10.1371/journal.pone.0173538 |
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