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A wild-type mouse-based model for the regression of inflammation in atherosclerosis
Atherosclerosis can be induced by the injection of a gain-of-function mutant of proprotein convertase subtilisin/kexin type 9 (PCSK9)–encoding adeno-associated viral vector (AAVmPCSK9), avoiding the need for knockout mice models, such as low-density lipoprotein receptor deficient mice. As regression...
Autores principales: | Peled, Michael, Nishi, Hitoo, Weinstock, Ada, Barrett, Tessa J., Zhou, Felix, Quezada, Alexandra, Fisher, Edward A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349694/ https://www.ncbi.nlm.nih.gov/pubmed/28291840 http://dx.doi.org/10.1371/journal.pone.0173975 |
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