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Sequestration of cholesterol within the host late endocytic pathway restricts liver-stage Plasmodium development
While lysosomes are degradative compartments and one of the defenses against invading pathogens, they are also hubs of metabolic activity. Late endocytic compartments accumulate around Plasmodium berghei liver-stage parasites during development, and whether this is a host defense strategy or active...
Autores principales: | Petersen, Wiebke, Stenzel, Werner, Silvie, Olivier, Blanz, Judith, Saftig, Paul, Matuschewski, Kai, Ingmundson, Alyssa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349780/ https://www.ncbi.nlm.nih.gov/pubmed/28122820 http://dx.doi.org/10.1091/mbc.E16-07-0531 |
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