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Sequestration of cholesterol within the host late endocytic pathway restricts liver-stage Plasmodium development

While lysosomes are degradative compartments and one of the defenses against invading pathogens, they are also hubs of metabolic activity. Late endocytic compartments accumulate around Plasmodium berghei liver-stage parasites during development, and whether this is a host defense strategy or active...

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Detalles Bibliográficos
Autores principales: Petersen, Wiebke, Stenzel, Werner, Silvie, Olivier, Blanz, Judith, Saftig, Paul, Matuschewski, Kai, Ingmundson, Alyssa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349780/
https://www.ncbi.nlm.nih.gov/pubmed/28122820
http://dx.doi.org/10.1091/mbc.E16-07-0531

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