Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification

Duplication of the centrosomes is a tightly regulated process. Abnormal centrosome numbers can impair cell division and cause changes in how cells migrate. Duplicated centrosomes are held together by a proteinaceous linker made up of rootletin filaments anchored to the centrioles by C-NAP1. This lin...

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Detalles Bibliográficos
Autores principales: Flanagan, Anne-Marie, Stavenschi, Elena, Basavaraju, Shivakumar, Gaboriau, David, Hoey, David A., Morrison, Ciaran G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349781/
https://www.ncbi.nlm.nih.gov/pubmed/28100636
http://dx.doi.org/10.1091/mbc.E16-05-0325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349781/
https://www.ncbi.nlm.nih.gov/pubmed/28100636
http://dx.doi.org/10.1091/mbc.E16-05-0325

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