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Munc13-4 functions as a Ca(2+) sensor for homotypic secretory granule fusion to generate endosomal exocytic vacuoles

Munc13-4 is a Ca(2+)-dependent SNARE (soluble N-ethylmaleimide–sensitive factor attachment protein receptor)- and phospholipid-binding protein that localizes to and primes secretory granules (SGs) for Ca(2+)-evoked secretion in various secretory cells. Studies in mast cell–like RBL-2H3 cells provide...

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Detalles Bibliográficos
Autores principales:	Woo, Sang Su, James, Declan J., Martin, Thomas F. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349786/ https://www.ncbi.nlm.nih.gov/pubmed/28100639 http://dx.doi.org/10.1091/mbc.E16-08-0617

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