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Pyruvate attenuates the anti-neoplastic effect of carnosine independently from oxidative phosphorylation

Here we analyzed whether the anti-neoplastic effect of carnosine, which inhibits glycolytic ATP production, can be antagonized by ATP production via oxidative phosphorylation fueled by pyruvate. Therefore, glioblastoma cells were cultivated in medium supplemented with glucose, galactose or pyruvate...

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Detalles Bibliográficos
Autores principales: Oppermann, Henry, Schnabel, Lutz, Meixensberger, Jürgen, Gaunitz, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349879/
https://www.ncbi.nlm.nih.gov/pubmed/27811375
http://dx.doi.org/10.18632/oncotarget.13039