Cargando…
Pyruvate attenuates the anti-neoplastic effect of carnosine independently from oxidative phosphorylation
Here we analyzed whether the anti-neoplastic effect of carnosine, which inhibits glycolytic ATP production, can be antagonized by ATP production via oxidative phosphorylation fueled by pyruvate. Therefore, glioblastoma cells were cultivated in medium supplemented with glucose, galactose or pyruvate...
Autores principales: | Oppermann, Henry, Schnabel, Lutz, Meixensberger, Jürgen, Gaunitz, Frank |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349879/ https://www.ncbi.nlm.nih.gov/pubmed/27811375 http://dx.doi.org/10.18632/oncotarget.13039 |
Ejemplares similares
-
Carnosine inhibits glioblastoma growth independent from PI3K/Akt/mTOR signaling
por: Oppermann, Henry, et al.
Publicado: (2019) -
Erythrocytes Prevent Degradation of Carnosine by Human Serum Carnosinase
por: Oppermann, Henry, et al.
Publicado: (2021) -
Non‐enzymatic reaction of carnosine and glyceraldehyde‐3‐phosphate accompanies metabolic changes of the pentose phosphate pathway
por: Oppermann, Henry, et al.
Publicado: (2019) -
Carnosine selectively inhibits migration of IDH-wildtype glioblastoma cells in a co-culture model with fibroblasts
por: Oppermann, Henry, et al.
Publicado: (2018) -
Metabolic response of glioblastoma cells associated with glucose withdrawal and pyruvate substitution as revealed by GC-MS
por: Oppermann, Henry, et al.
Publicado: (2016)