NT1721, a novel epidithiodiketopiperazine, exhibits potent in vitro and in vivo efficacy against acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive malignancy characterized by heterogeneous genetic and epigenetic changes in hematopoietic progenitors that lead to abnormal self-renewal and proliferation. Despite high initial remission rates, prognosis remains poor for most AML patients, especially for...

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Detalles Bibliográficos
Autores principales: Kowolik, Claudia M., Lin, Min, Xie, Jun, Overman, Larry E., Horne, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349906/
https://www.ncbi.nlm.nih.gov/pubmed/27863389
http://dx.doi.org/10.18632/oncotarget.13364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349906/
https://www.ncbi.nlm.nih.gov/pubmed/27863389
http://dx.doi.org/10.18632/oncotarget.13364

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