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Suppression of hepatic stellate cell activation through downregulation of gremlin1 expression by the miR-23b/27b cluster
The imbalance between transforming growth factor β and bone morphogenetic protein 7 signaling pathways is a critical step in promoting hepatic stellate cell activation during hepatic fibrogenesis. Gremlin1 may impair the balance. Something remains unclear about the regulatory mechanisms of gremlin1...
Autores principales: | Zeng, Xian-Yi, Zhang, Yan-Qiong, He, Xiao-Min, Wan, Lin-Yan, Wang, Hu, Ni, Yi-Ran, Wang, Jie, Wu, Jiang-Feng, Liu, Chang-Bai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349907/ https://www.ncbi.nlm.nih.gov/pubmed/27863390 http://dx.doi.org/10.18632/oncotarget.13365 |
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