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Intratumoral heterogeneity and chemoresistance in nonseminomatous germ cell tumor of the testis
BACKGROUND: Nonseminomatous germ cell tumor of the testis (NSGCT) is largely curable. However, a small group of patients develop refractory disease. We investigated the hypothesis that intratumoral heterogeneity contributes to the emergence of chemoresistance and the development of refractory tumor...
Autores principales: | Bilen, Mehmet Asim, Hess, Kenneth R., Campbell, Matthew T., Wang, Jennifer, Broaddus, Russell R., Karam, Jose A., Ward, John F., Wood, Christopher G., Choi, Seungtaek L., Rao, Priya, Zhang, Miao, Naing, Aung, General, Rosale, Cauley, Diana H., Lin, Sue-Hwa, Logothetis, Christopher J., Pisters, Louis L., Tu, Shi-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349913/ https://www.ncbi.nlm.nih.gov/pubmed/27861143 http://dx.doi.org/10.18632/oncotarget.13380 |
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