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Gene and microRNA modulation upon trabectedin treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line
Intrahepatic cholangiocarcinoma (ICC) is an aggressive and lethal malignancy with limited therapeutic options. Trabectedin has a high antitumor activity in preclinical models of biliary tract carcinoma (BTC), being a promising alternative treatment. Here, we studied the effect of trabectedin at tran...
Autores principales: | Peraldo Neia, Caterina, Cavalloni, Giuliana, Chiorino, Giovanna, Ostano, Paola, Aglietta, Massimo, Leone, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349952/ https://www.ncbi.nlm.nih.gov/pubmed/27902465 http://dx.doi.org/10.18632/oncotarget.13575 |
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