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The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport
2-hydroxyoleic acid (OHOA, Minerval(®)) is an example of a substance used for membrane lipid therapy, where the cellular membranes rather than specific proteins constitute the therapeutical target. OHOA is thought to mediate its anti-tumor effect by affecting the biophysical properties of membranes,...
Autores principales: | Torgersen, Maria L., Klokk, Tove Irene, Kavaliauskiene, Simona, Klose, Christian, Simons, Kai, Skotland, Tore, Sandvig, Kirsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349960/ https://www.ncbi.nlm.nih.gov/pubmed/27894086 http://dx.doi.org/10.18632/oncotarget.13508 |
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