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VENTX induces expansion of primitive erythroid cells and contributes to the development of acute myeloid leukemia in mice
Homeobox genes are key regulators in normal and malignant hematopoiesis. The human Vent-like homeobox gene VENTX, a putative homolog of the Xenopus laevis Xvent-2 gene, was shown to be highly expressed in normal myeloid cells and in patients with acute myeloid leukemia. We now demonstrate that const...
Autores principales: | Gentner, Eva, Vegi, Naidu M., Mulaw, Medhanie A., Mandal, Tamoghna, Bamezai, Shiva, Claus, Rainer, Tasdogan, Alpaslan, Quintanilla-Martinez, Leticia, Grunenberg, Alexander, Döhner, Konstanze, Döhner, Hartmut, Bullinger, Lars, Haferlach, Torsten, Buske, Christian, Rawat, Vijay P.S., Feuring-Buske, Michaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349961/ https://www.ncbi.nlm.nih.gov/pubmed/27888632 http://dx.doi.org/10.18632/oncotarget.13563 |
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