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Tracing anti-cancer and cancer-promoting actions of all-trans retinoic acid in breast cancer to a RARa epigenetic mechanism of mammary epithelial cell fate
A hallmark of cancer cells is the ability to evade the growth inhibitory/pro-apoptotic action of physiological all-trans retinoic acid (RA) signal, the bioactive derivative of Vitamin A. However, as we and others reported, RA can also promote cancer cell growth and invasion. Here we show that antica...
Autores principales: | Rossetti, Stefano, Ren, MingQiang, Visconti, Nicolo, Corlazzoli, Francesca, Gagliostro, Vincenzo, Somenzi, Giulia, Yao, Jin, Sun, Yijun, Sacchi, Nicoletta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349971/ https://www.ncbi.nlm.nih.gov/pubmed/27894085 http://dx.doi.org/10.18632/oncotarget.13500 |
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