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RhoA regulates resistance to irinotecan by regulating membrane transporter and apoptosis signaling in colorectal cancer

Colorectal cancer (CRC) is a major cause of mortality and morbidity worldwide. While surgery remains the mainstay of treatment in early stage CRC, chemotherapy is usually given to prolong the overall survival and improve the quality of life for metastatic colorectal cancer (mCRC). But drug resistanc...

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Detalles Bibliográficos
Autores principales:	Ruihua, Huang, Mengyi, Zhang, Chong, Zhao, Meng, Qiu, Xin, Ma, Qiulin, Tang, Feng, Bi, Ming, Liu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349977/ https://www.ncbi.nlm.nih.gov/pubmed/27888624 http://dx.doi.org/10.18632/oncotarget.13548

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