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Activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway in human lung cancer cells by the new synthetic flavonoid, LZ-205

It has been shown that flavonoids have anti-tumor activity. In this study, LZ-205, a newly synthesized flavonoid, was found to be effective in inducing apoptosis in human lung cancer cells in vivo and in vitro. Mechanistically, LZ-205 triggers reactive oxygen species (ROS)-induced endoplasmic reticu...

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Detalles Bibliográficos
Autores principales:	Zhang, Yi, Xu, Xuefen, Li, Wei, Miao, Hanchi, Huang, Shaoliang, Zhou, Yuxin, Sun, Yang, Li, Zhiyu, Guo, Qinglong, Zhao, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349986/ https://www.ncbi.nlm.nih.gov/pubmed/27895312 http://dx.doi.org/10.18632/oncotarget.13535

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