Cargando…
Toll-like receptor 9 expression is associated with breast cancer sensitivity to the growth inhibitory effects of bisphosphonates in vitro and in vivo
Bisphosphonates are standard treatments for bone metastases. When given in the adjuvant setting, they reduce breast cancer mortality and recurrence in bone but only among post-menopausal patients. Optimal drug use would require biomarker-based patient selection. Such biomarkers are not yet in clinic...
Autores principales: | Sandholm, Jouko, Lehtimäki, Jaakko, Ishizu, Tamiko, Velu, Sadanandan E., Clark, Jeremy, Härkönen, Pirkko, Jukkola-Vuorinen, Arja, Schrey, Aleksi, Harris, Kevin W., Tuomela, Johanna M., Selander, Katri S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349995/ https://www.ncbi.nlm.nih.gov/pubmed/27888633 http://dx.doi.org/10.18632/oncotarget.13570 |
Ejemplares similares
-
Alendronate-induced disruption of actin cytoskeleton and inhibition of migration/invasion are associated with cofilin downregulation in PC-3 prostate cancer cells
por: Virtanen, Sanna S., et al.
Publicado: (2018) -
Toll-Like Receptor 9 in Breast Cancer
por: Sandholm, Jouko, et al.
Publicado: (2014) -
Hypoxia regulates Toll-like receptor-9 expression and invasive function in human brain cancer cells in vitro
por: SANDHOLM, JOUKO, et al.
Publicado: (2014) -
Chloroquine has tumor-inhibitory and tumor-promoting effects in triple-negative breast cancer
por: TUOMELA, JOHANNA, et al.
Publicado: (2013) -
CD73 facilitates EMT progression and promotes lung metastases in triple-negative breast cancer
por: Petruk, Nataliia, et al.
Publicado: (2021)