Increased Circulating T Follicular Helper Cells Are Inhibited by Rituximab in Neuromyelitis Optica Spectrum Disorder

Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune disease of the central nervous system. The existence of autoantibody targeting aquaporin-4 (AQP4-Ab) indicates the involvement of humoral immunity in the pathogenesis of this disease. Rituximab (RTX), a monoclonal antibody against...

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Detalles Bibliográficos
Autores principales: Zhao, Cong, Li, Hong-Zeng, Zhao, Dai-Di, Ma, Chao, Wu, Fang, Bai, Ya-Nan, Zhang, Min, Li, Zhu-Yi, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350120/
https://www.ncbi.nlm.nih.gov/pubmed/28360886
http://dx.doi.org/10.3389/fneur.2017.00104

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