Bosutinib Therapy Ameliorates Lung Inflammation and Fibrosis in Experimental Silicosis

Silicosis is an occupational lung disease for which no effective therapy exists. We hypothesized that bosutinib, a tyrosine kinase inhibitor, might ameliorate inflammatory responses, attenuate pulmonary fibrosis, and thus improve lung function in experimental silicosis. For this purpose, we investig...

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Detalles Bibliográficos
Autores principales: Carneiro, Priscila J., Clevelario, Amanda L., Padilha, Gisele A., Silva, Johnatas D., Kitoko, Jamil Z., Olsen, Priscilla C., Capelozzi, Vera L., Rocco, Patricia R. M., Cruz, Fernanda F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350127/
https://www.ncbi.nlm.nih.gov/pubmed/28360865
http://dx.doi.org/10.3389/fphys.2017.00159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350127/
https://www.ncbi.nlm.nih.gov/pubmed/28360865
http://dx.doi.org/10.3389/fphys.2017.00159

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