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A short history of heme dioxygenases: rise, fall and rise again
It is well established that there are two different classes of enzymes—tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO)—that catalyse the O(2)-dependent oxidation of l-tryptophan to N-formylkynurenine. But it was not always so. This perspective presents a short history of the e...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350241/ https://www.ncbi.nlm.nih.gov/pubmed/27909919 http://dx.doi.org/10.1007/s00775-016-1412-5 |