Cargando…

High‐fat diet induces protein kinase A and G‐protein receptor kinase phosphorylation of β(2)‐adrenergic receptor and impairs cardiac adrenergic reserve in animal hearts

KEY POINTS: Patients with diabetes show a blunted cardiac inotropic response to β‐adrenergic stimulation despite normal cardiac contractile reserve. Acute insulin stimulation impairs β‐adrenergically induced contractile function in isolated cardiomyocytes and Langendorff‐perfused hearts. In this stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fu, Qin, Hu, Yuting, Wang, Qingtong, Liu, Yongming, Li, Ning, Xu, Bing, Kim, Sungjin, Chiamvimonvat, Nipavan, Xiang, Yang K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Cardiovascular
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350441/ https://www.ncbi.nlm.nih.gov/pubmed/27983752 http://dx.doi.org/10.1113/JP273314

Ejemplares similares

The insulin receptor family and protein kinase B (Akt) are activated in the heart by alkaline pH and α(1)-adrenergic receptors
por: Meijles, Daniel N., et al.
Publicado: (2021)

Protein-Protein Interactions at the Adrenergic Receptors
por: Cotecchia, Susanna, et al.
Publicado: (2012)

Gi-protein-coupled β (1)-adrenergic receptor: re-understanding the selectivity of β (1)-adrenergic receptor to G protein : Gi-protein-coupled β (1)-adrenergic receptor
por: Chen, Hao, et al.
Publicado: (2022)

Calcium/calmodulin‐dependent kinase II and nitric oxide synthase 1‐dependent modulation of ryanodine receptors during β‐adrenergic stimulation is restricted to the dyadic cleft
por: Dries, Eef, et al.
Publicado: (2016)

Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes
por: Hong, Shangyu, et al.
Publicado: (2018)

Raf kinase inhibitor protein: lessons of a better way for β‐adrenergic receptor activation in the heart
por: Lorenz, Kristina, et al.
Publicado: (2017)

Aldosterone Jeopardizes Myocardial Insulin and β-Adrenergic Receptor Signaling via G Protein-Coupled Receptor Kinase 2
por: Cannavo, Alessandro, et al.
Publicado: (2019)

Cardiac myosin binding protein-C Ser(302) phosphorylation regulates cardiac β-adrenergic reserve
por: Mamidi, Ranganath, et al.
Publicado: (2017)

Bidirectional Role of β2-Adrenergic Receptor in Autoimmune Diseases
por: Wu, Li, et al.
Publicado: (2018)

Beta-1-Adrenergic Receptor Antibodies in Acute Coronary Syndrome: Is Less Sometimes More?
por: Ernst, Diana, et al.
Publicado: (2018)

β-Adrenergic Receptor Desensitization/Down-Regulation in Heart Failure: A Friend or Foe?
por: Mahmood, Abrahim, et al.
Publicado: (2022)

Role of adrenergic receptors in shock
por: Geevarghese, Mathew, et al.
Publicado: (2023)

Regulation of heart rate following genetic deletion of the ß1 adrenergic receptor in larval zebrafish
por: Joyce, William, et al.
Publicado: (2022)

The Regulator of G Protein Signaling Homologous Domain of G Protein-Coupled Receptor Kinase 2 Mediates Short-Term Desensitization of β3-Adrenergic Receptor
por: Echeverría, Emiliana, et al.
Publicado: (2020)

Beta-Adrenergic Antagonist Tolerance in Amyloid Cardiomyopathy
por: Ramsell, Stuart, et al.
Publicado: (2022)

SAT-078 Adrenergic Receptor Regulation of Intracellular Calcium in Human Adrenocortical Carcinoma HAC15 Cells
por: Malaiyandi, Latha, et al.
Publicado: (2019)

Probing the stoichiometry of β2-adrenergic receptor phosphorylation by targeted mass spectrometry
por: Gao, Shujuan, et al.
Publicado: (2014)

Prognostic Value of β1 Adrenergic Receptor Autoantibody and Soluble Suppression of Tumorigenicity-2 in Patients With Acutely Decompensated Heart Failure
por: Sun, Yanxiang, et al.
Publicado: (2022)

Crystal Structure of the β(2)Adrenergic Receptor-Gs protein complex
por: Rasmussen, Søren G.F., et al.
Publicado: (2011)

G(s) protein peptidomimetics as allosteric modulators of the β(2)-adrenergic receptor
por: Boyhus, Lotte-Emilie, et al.
Publicado: (2018)

α(2)-Adrenergic Disruption of β Cell BDNF-TrkB Receptor Tyrosine Kinase Signaling
por: Kalwat, Michael A., et al.
Publicado: (2020)

Protein kinase Cζ regulates phospholipase D activity in rat-1 fibroblasts expressing the α(1A )adrenergic receptor
por: Parmentier, Jean-Hugues, et al.
Publicado: (2004)

Exercise Training Attenuates Acute β-Adrenergic Receptor Activation-Induced Cardiac Inflammation via the Activation of AMP-Activated Protein Kinase
por: Zhang, Mi, et al.
Publicado: (2023)

LRRC10 (Leucine‐Rich Repeat Containing Protein 10) and REEP5 (Receptor Accessory Protein 5) as Novel Regulators of Cardiac Excitation‐Contraction Coupling Structure and Function
por: Chiamvimonvat, Nipavan, et al.
Publicado: (2018)

Attenuated β-adrenergic response in calcium/calmodulin-dependent protein kinase IV-knockout mice
por: Murakami, Manabu, et al.
Publicado: (2021)

G protein-coupled receptor kinase 2 regulating β2-adrenergic receptor signaling in M2-polarized macrophages contributes to hepatocellular carcinoma progression
por: Wu, Jing-Jing, et al.
Publicado: (2019)

Phosphoinositide 3-kinase regulates β2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/β-arrestin complex
por: Naga Prasad, Sathyamangla V., et al.
Publicado: (2002)

Determinants Present in the Receptor Carboxy Tail Are Responsible for Differences in Subtype-Specific Coupling of β-Adrenergic Receptors to Phosphoinositide 3-Kinase
por: Simard, Julie, et al.
Publicado: (2009)

Internalization Dissociates β(2)-Adrenergic Receptors
por: Lan, Tien-Hung, et al.
Publicado: (2011)

β-Adrenergic Receptor Signaling in Prostate Cancer
por: Braadland, Peder Rustøen, et al.
Publicado: (2015)

Optodynamic simulation of β-adrenergic receptor signalling
por: Siuda, Edward R., et al.
Publicado: (2015)

β-Adrenergic Receptor and Insulin Resistance in the Heart
por: Mangmool, Supachoke, et al.
Publicado: (2017)

Role of adrenergic receptor signalling in neuroimmune communication
por: Chhatar, Sushanta, et al.
Publicado: (2021)

The Role of Beta-Adrenergic Receptors in Depression and Resilience
por: Zhang, Hongxing, et al.
Publicado: (2022)

Muscle Plasticity and β(2)-Adrenergic Receptors: Adaptive Responses of β(2)-Adrenergic Receptor Expression to Muscle Hypertrophy and Atrophy
por: Sato, Shogo, et al.
Publicado: (2011)

Phosphodiesterase 4D disruption causes β2 adrenergic receptors to behave like β1 adrenergic receptors in vivo
por: Pearl, N, et al.
Publicado: (2006)

Cardiac β(2)-Adrenergic Receptor Phosphorylation at Ser(355/356) Regulates Receptor Internalization and Functional Resensitization
por: Fan, Xiaofang, et al.
Publicado: (2016)

Phosphodiesterase 5 Associates With β2 Adrenergic Receptor to Modulate Cardiac Function in Type 2 Diabetic Hearts
por: West, Toni M., et al.
Publicado: (2019)

Heterologous Facilitation of G Protein-Activated K(+) Channels by β-Adrenergic Stimulation via Camp-Dependent Protein Kinase
por: Müllner, Carmen, et al.
Publicado: (2000)

Phosphorylation of the ryanodine receptor 2 at serine 2030 is required for a complete β-adrenergic response
por: Potenza, Duilio M., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_s3342flgad68kto3orvjmp96lg