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4-Nitro styrylquinoline is an antimalarial inhibiting multiple stages of Plasmodium falciparum asexual life cycle

Drugs against malaria are losing their effectiveness because of emerging drug resistance. This underscores the need for novel therapeutic options for malaria with mechanism of actions distinct from current antimalarials. To identify novel pharmacophores against malaria we have screened compounds con...

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Detalles Bibliográficos
Autores principales: Roberts, Bracken F., Zheng, Yongsheng, Cleaveleand, Jacob, Lee, Sukjun, Lee, Eunyoung, Ayong, Lawrence, Yuan, Yu, Chakrabarti, Debopam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350499/
https://www.ncbi.nlm.nih.gov/pubmed/28285258
http://dx.doi.org/10.1016/j.ijpddr.2017.02.002

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