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Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation

Dendritic cells (DCs) promote either tolerogenic or immunogenic T cell responses, the latter upon sensing microbes. Using an in vitro system, we analyzed transcriptional determinants that enable mature DCs to direct these opposing T cell outcomes. In the absence of microbial products, the transcript...

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Detalles Bibliográficos
Autores principales:	Vander Lugt, Bryan, Riddell, Jeremy, Khan, Aly A., Hackney, Jason A., Lesch, Justin, DeVoss, Jason, Weirauch, Matthew T., Singh, Harinder, Mellman, Ira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350508/ https://www.ncbi.nlm.nih.gov/pubmed/28130292 http://dx.doi.org/10.1083/jcb.201512012

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