TOPBP1(Dpb11) plays a conserved role in homologous recombination DNA repair through the coordinated recruitment of 53BP1(Rad9)

Genome maintenance and cancer suppression require homologous recombination (HR) DNA repair. In yeast and mammals, the scaffold protein TOPBP1(Dpb11) has been implicated in HR, although its precise function and mechanism of action remain elusive. In this study, we show that yeast Dpb11 plays an antag...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Cussiol, José Renato, Dibitetto, Diego, Sims, Jennie Rae, Twayana, Shyam, Weiss, Robert Samuel, Freire, Raimundo, Marini, Federica, Pellicioli, Achille, Smolka, Marcus Bustamante
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350513/
https://www.ncbi.nlm.nih.gov/pubmed/28228534
http://dx.doi.org/10.1083/jcb.201607031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350513/
https://www.ncbi.nlm.nih.gov/pubmed/28228534
http://dx.doi.org/10.1083/jcb.201607031

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