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Human centromeric CENP-A chromatin is a homotypic, octameric nucleosome at all cell cycle points

Chromatin assembled with centromere protein A (CENP-A) is the epigenetic mark of centromere identity. Using new reference models, we now identify sites of CENP-A and histone H3.1 binding within the megabase, α-satellite repeat–containing centromeres of 23 human chromosomes. The overwhelming majority...

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Detalles Bibliográficos
Autores principales: Nechemia-Arbely, Yael, Fachinetti, Daniele, Miga, Karen H., Sekulic, Nikolina, Soni, Gautam V., Kim, Dong Hyun, Wong, Adeline K., Lee, Ah Young, Nguyen, Kristen, Dekker, Cees, Ren, Bing, Black, Ben E., Cleveland, Don W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350519/
https://www.ncbi.nlm.nih.gov/pubmed/28235947
http://dx.doi.org/10.1083/jcb.201608083