TorsinA regulates the LINC to moving nuclei

How LINC complexes are regulated to connect nuclei to the cytoskeleton during nuclear migration is unknown. Saunders et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201507113) show that the AAA+ ATPase torsinA and its partner LAP1 are required for nuclear migration during fibroblast polariza...

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Detalles Bibliográficos
Autores principales: Starr, Daniel A., Rose, Lesilee S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350524/
https://www.ncbi.nlm.nih.gov/pubmed/28242746
http://dx.doi.org/10.1083/jcb.201701054
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author Starr, Daniel A.
Rose, Lesilee S.
author_facet Starr, Daniel A.
Rose, Lesilee S.
author_sort Starr, Daniel A.
collection PubMed
description How LINC complexes are regulated to connect nuclei to the cytoskeleton during nuclear migration is unknown. Saunders et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201507113) show that the AAA+ ATPase torsinA and its partner LAP1 are required for nuclear migration during fibroblast polarization by mediating the dynamics of LINC complexes.
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spelling pubmed-53505242017-09-06 TorsinA regulates the LINC to moving nuclei Starr, Daniel A. Rose, Lesilee S. J Cell Biol Commentary How LINC complexes are regulated to connect nuclei to the cytoskeleton during nuclear migration is unknown. Saunders et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201507113) show that the AAA+ ATPase torsinA and its partner LAP1 are required for nuclear migration during fibroblast polarization by mediating the dynamics of LINC complexes. The Rockefeller University Press 2017-03-06 /pmc/articles/PMC5350524/ /pubmed/28242746 http://dx.doi.org/10.1083/jcb.201701054 Text en © 2017 Starr and Rose http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Starr, Daniel A.
Rose, Lesilee S.
TorsinA regulates the LINC to moving nuclei
title TorsinA regulates the LINC to moving nuclei
title_full TorsinA regulates the LINC to moving nuclei
title_fullStr TorsinA regulates the LINC to moving nuclei
title_full_unstemmed TorsinA regulates the LINC to moving nuclei
title_short TorsinA regulates the LINC to moving nuclei
title_sort torsina regulates the linc to moving nuclei
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350524/
https://www.ncbi.nlm.nih.gov/pubmed/28242746
http://dx.doi.org/10.1083/jcb.201701054
work_keys_str_mv AT starrdaniela torsinaregulatesthelinctomovingnuclei
AT roselesilees torsinaregulatesthelinctomovingnuclei

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