The heat shock factor HSF1 juggles protein quality control and metabolic regulation

Transcriptional regulators often act as central hubs to integrate multiple nutrient and stress signals. In this issue, Qiao et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607091) demonstrate how heat shock factor 1 (HSF1) uncouples metabolic control from proteostatic regulation and unvei...

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Detalles Bibliográficos
Autor principal: Cantó, Carles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350526/
https://www.ncbi.nlm.nih.gov/pubmed/28183718
http://dx.doi.org/10.1083/jcb.201701093
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author Cantó, Carles
author_facet Cantó, Carles
author_sort Cantó, Carles
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description Transcriptional regulators often act as central hubs to integrate multiple nutrient and stress signals. In this issue, Qiao et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607091) demonstrate how heat shock factor 1 (HSF1) uncouples metabolic control from proteostatic regulation and unveils HSF1 as a critical transcriptional regulator of NAD(+) metabolism.
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spelling pubmed-53505262017-09-06 The heat shock factor HSF1 juggles protein quality control and metabolic regulation Cantó, Carles J Cell Biol Commentary Transcriptional regulators often act as central hubs to integrate multiple nutrient and stress signals. In this issue, Qiao et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607091) demonstrate how heat shock factor 1 (HSF1) uncouples metabolic control from proteostatic regulation and unveils HSF1 as a critical transcriptional regulator of NAD(+) metabolism. The Rockefeller University Press 2017-03-06 /pmc/articles/PMC5350526/ /pubmed/28183718 http://dx.doi.org/10.1083/jcb.201701093 Text en © 2017 Cantó http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Cantó, Carles
The heat shock factor HSF1 juggles protein quality control and metabolic regulation
title The heat shock factor HSF1 juggles protein quality control and metabolic regulation
title_full The heat shock factor HSF1 juggles protein quality control and metabolic regulation
title_fullStr The heat shock factor HSF1 juggles protein quality control and metabolic regulation
title_full_unstemmed The heat shock factor HSF1 juggles protein quality control and metabolic regulation
title_short The heat shock factor HSF1 juggles protein quality control and metabolic regulation
title_sort heat shock factor hsf1 juggles protein quality control and metabolic regulation
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350526/
https://www.ncbi.nlm.nih.gov/pubmed/28183718
http://dx.doi.org/10.1083/jcb.201701093
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