Fragile phagocytes: FMRP positively regulates engulfment activity

Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O’Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogas...

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Detalles Bibliográficos
Autor principal: Logan, Mary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350528/
https://www.ncbi.nlm.nih.gov/pubmed/28228533
http://dx.doi.org/10.1083/jcb.201702034
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author Logan, Mary A.
author_facet Logan, Mary A.
author_sort Logan, Mary A.
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description Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O’Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development.
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spelling pubmed-53505282017-09-06 Fragile phagocytes: FMRP positively regulates engulfment activity Logan, Mary A. J Cell Biol Commentary Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O’Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development. The Rockefeller University Press 2017-03-06 /pmc/articles/PMC5350528/ /pubmed/28228533 http://dx.doi.org/10.1083/jcb.201702034 Text en © 2017 Logan http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Logan, Mary A.
Fragile phagocytes: FMRP positively regulates engulfment activity
title Fragile phagocytes: FMRP positively regulates engulfment activity
title_full Fragile phagocytes: FMRP positively regulates engulfment activity
title_fullStr Fragile phagocytes: FMRP positively regulates engulfment activity
title_full_unstemmed Fragile phagocytes: FMRP positively regulates engulfment activity
title_short Fragile phagocytes: FMRP positively regulates engulfment activity
title_sort fragile phagocytes: fmrp positively regulates engulfment activity
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350528/
https://www.ncbi.nlm.nih.gov/pubmed/28228533
http://dx.doi.org/10.1083/jcb.201702034
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