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An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional Screening
[Image: see text] DNA-encoded synthesis is rekindling interest in combinatorial compound libraries for drug discovery and in technology for automated and quantitative library screening. Here, we disclose a microfluidic circuit that enables functional screens of DNA-encoded compound beads. The device...
Autores principales: | MacConnell, Andrew B., Price, Alexander K., Paegel, Brian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2017
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350604/ https://www.ncbi.nlm.nih.gov/pubmed/28199790 http://dx.doi.org/10.1021/acscombsci.6b00192 |
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