Sex differences in gout characteristics: tailoring care for women and men

BACKGROUND: To characterize the differences between women and men with gout. METHODS: We analyzed a US national cohort of gout patients cared for by rheumatologists. RESULTS: Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater...

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Detalles Bibliográficos
Autores principales: Harrold, Leslie R., Etzel, Carol J., Gibofsky, Allan, Kremer, Joel M., Pillinger, Michael H., Saag, Kenneth G., Schlesinger, Naomi, Terkeltaub, Robert, Cox, Vanessa, Greenberg, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351188/
https://www.ncbi.nlm.nih.gov/pubmed/28292303
http://dx.doi.org/10.1186/s12891-017-1465-9
Descripción
Sumario:BACKGROUND: To characterize the differences between women and men with gout. METHODS: We analyzed a US national cohort of gout patients cared for by rheumatologists. RESULTS: Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Risk factors for gout differed with women more often taking diuretics (p < 0.001), while men more frequently had dietary triggers (p < 0.05). CONCLUSIONS: The profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12891-017-1465-9) contains supplementary material, which is available to authorized users.

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