Sex differences in gout characteristics: tailoring care for women and men

BACKGROUND: To characterize the differences between women and men with gout. METHODS: We analyzed a US national cohort of gout patients cared for by rheumatologists. RESULTS: Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater...

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Autores principales: Harrold, Leslie R., Etzel, Carol J., Gibofsky, Allan, Kremer, Joel M., Pillinger, Michael H., Saag, Kenneth G., Schlesinger, Naomi, Terkeltaub, Robert, Cox, Vanessa, Greenberg, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351188/
https://www.ncbi.nlm.nih.gov/pubmed/28292303
http://dx.doi.org/10.1186/s12891-017-1465-9
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author Harrold, Leslie R.
Etzel, Carol J.
Gibofsky, Allan
Kremer, Joel M.
Pillinger, Michael H.
Saag, Kenneth G.
Schlesinger, Naomi
Terkeltaub, Robert
Cox, Vanessa
Greenberg, Jeffrey D.
author_facet Harrold, Leslie R.
Etzel, Carol J.
Gibofsky, Allan
Kremer, Joel M.
Pillinger, Michael H.
Saag, Kenneth G.
Schlesinger, Naomi
Terkeltaub, Robert
Cox, Vanessa
Greenberg, Jeffrey D.
author_sort Harrold, Leslie R.
collection PubMed
description BACKGROUND: To characterize the differences between women and men with gout. METHODS: We analyzed a US national cohort of gout patients cared for by rheumatologists. RESULTS: Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Risk factors for gout differed with women more often taking diuretics (p < 0.001), while men more frequently had dietary triggers (p < 0.05). CONCLUSIONS: The profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12891-017-1465-9) contains supplementary material, which is available to authorized users.
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spelling pubmed-53511882017-03-17 Sex differences in gout characteristics: tailoring care for women and men Harrold, Leslie R. Etzel, Carol J. Gibofsky, Allan Kremer, Joel M. Pillinger, Michael H. Saag, Kenneth G. Schlesinger, Naomi Terkeltaub, Robert Cox, Vanessa Greenberg, Jeffrey D. BMC Musculoskelet Disord Research Article BACKGROUND: To characterize the differences between women and men with gout. METHODS: We analyzed a US national cohort of gout patients cared for by rheumatologists. RESULTS: Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Risk factors for gout differed with women more often taking diuretics (p < 0.001), while men more frequently had dietary triggers (p < 0.05). CONCLUSIONS: The profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12891-017-1465-9) contains supplementary material, which is available to authorized users. BioMed Central 2017-03-14 /pmc/articles/PMC5351188/ /pubmed/28292303 http://dx.doi.org/10.1186/s12891-017-1465-9 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Harrold, Leslie R.
Etzel, Carol J.
Gibofsky, Allan
Kremer, Joel M.
Pillinger, Michael H.
Saag, Kenneth G.
Schlesinger, Naomi
Terkeltaub, Robert
Cox, Vanessa
Greenberg, Jeffrey D.
Sex differences in gout characteristics: tailoring care for women and men
title Sex differences in gout characteristics: tailoring care for women and men
title_full Sex differences in gout characteristics: tailoring care for women and men
title_fullStr Sex differences in gout characteristics: tailoring care for women and men
title_full_unstemmed Sex differences in gout characteristics: tailoring care for women and men
title_short Sex differences in gout characteristics: tailoring care for women and men
title_sort sex differences in gout characteristics: tailoring care for women and men
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351188/
https://www.ncbi.nlm.nih.gov/pubmed/28292303
http://dx.doi.org/10.1186/s12891-017-1465-9
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