Ciprofloxacin induced acute generallised exanthematous pustulosis

Acute generalized exanthematous pustulosis (AGEP) is an uncommon and self-limiting skin rash commonly caused by drugs and is characterized by the acute onset of fever, pustulosis, and neutrophilia from 4 to 10 days after the drug intake. We describe a case of AGEP in a 61-year-old woman that was hos...

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Autores principales: Foti, Caterina, Romita, Paolo, Zanframundo, Giovanni, Mastrolonardo, Mario, Angelini, Gianni, Calogiuri, Gianfranco, Nettis, Eustacchio, Bonamonte, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351224/
https://www.ncbi.nlm.nih.gov/pubmed/28458435
http://dx.doi.org/10.4103/0253-7613.201014
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author Foti, Caterina
Romita, Paolo
Zanframundo, Giovanni
Mastrolonardo, Mario
Angelini, Gianni
Calogiuri, Gianfranco
Nettis, Eustacchio
Bonamonte, Domenico
author_facet Foti, Caterina
Romita, Paolo
Zanframundo, Giovanni
Mastrolonardo, Mario
Angelini, Gianni
Calogiuri, Gianfranco
Nettis, Eustacchio
Bonamonte, Domenico
author_sort Foti, Caterina
collection PubMed
description Acute generalized exanthematous pustulosis (AGEP) is an uncommon and self-limiting skin rash commonly caused by drugs and is characterized by the acute onset of fever, pustulosis, and neutrophilia from 4 to 10 days after the drug intake. We describe a case of AGEP in a 61-year-old woman that was hospitalized for the acute onset of fever, erythroderma, and pustulosis. Clinical history revealed that she had been treating a bacterial inguinal intertrigo for 4 days with ciprofloxacin 500 mg tablets twice daily and desloratadine 5 mg tablet once daily. To the best of our knowledge, this is the third reported case of AGEP caused by ciprofloxacin, supporting two other previous reports.
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spelling pubmed-53512242017-04-28 Ciprofloxacin induced acute generallised exanthematous pustulosis Foti, Caterina Romita, Paolo Zanframundo, Giovanni Mastrolonardo, Mario Angelini, Gianni Calogiuri, Gianfranco Nettis, Eustacchio Bonamonte, Domenico Indian J Pharmacol Drug Watch Acute generalized exanthematous pustulosis (AGEP) is an uncommon and self-limiting skin rash commonly caused by drugs and is characterized by the acute onset of fever, pustulosis, and neutrophilia from 4 to 10 days after the drug intake. We describe a case of AGEP in a 61-year-old woman that was hospitalized for the acute onset of fever, erythroderma, and pustulosis. Clinical history revealed that she had been treating a bacterial inguinal intertrigo for 4 days with ciprofloxacin 500 mg tablets twice daily and desloratadine 5 mg tablet once daily. To the best of our knowledge, this is the third reported case of AGEP caused by ciprofloxacin, supporting two other previous reports. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5351224/ /pubmed/28458435 http://dx.doi.org/10.4103/0253-7613.201014 Text en Copyright: © 2017 Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Drug Watch
Foti, Caterina
Romita, Paolo
Zanframundo, Giovanni
Mastrolonardo, Mario
Angelini, Gianni
Calogiuri, Gianfranco
Nettis, Eustacchio
Bonamonte, Domenico
Ciprofloxacin induced acute generallised exanthematous pustulosis
title Ciprofloxacin induced acute generallised exanthematous pustulosis
title_full Ciprofloxacin induced acute generallised exanthematous pustulosis
title_fullStr Ciprofloxacin induced acute generallised exanthematous pustulosis
title_full_unstemmed Ciprofloxacin induced acute generallised exanthematous pustulosis
title_short Ciprofloxacin induced acute generallised exanthematous pustulosis
title_sort ciprofloxacin induced acute generallised exanthematous pustulosis
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351224/
https://www.ncbi.nlm.nih.gov/pubmed/28458435
http://dx.doi.org/10.4103/0253-7613.201014
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