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Hypothesizing that, A Pro-Dopamine Regulator (KB220Z) Should Optimize, but Not Hyper-Activate the Activity of Trace Amine-Associated Receptor 1 (TAAR-1) and Induce Anti-Craving of Psychostimulants in the Long-Term
Unlike other drugs of abuse such as alcohol, nicotine, opiates/opioids, the FDA has not approved any agent to treat psychostimulant dependence. Certainly, it is widely acceptable that dopaminergic signaling is a key factor in both the initiation and continued motivation to abuse this class of stimul...
Autores principales: | Blum, Kenneth, Badgaiyan, Rajendra D., Braverman, Eric R., Dushaj, Kristina, Li, Mona, Thanos, Peter K., Demetrovics, Zsolt, Febo, Marcelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351297/ https://www.ncbi.nlm.nih.gov/pubmed/28317038 http://dx.doi.org/10.17756/jrdsas.2016-023 |
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