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IκB-α: At the crossroad between oncogenic and tumor-suppressive signals
Nuclear factor κB (NF-κB) is an essential component of tumorigenesis and resistance to cancer treatments. NFKB inhibitor α (IκB-α) acts as a negative regulator of the classical NF-κB pathway through its ability to maintain the presence of NF-κB in the cytoplasm. However, IκB-α is also able to form a...
Autores principales: | Morotti, Alessandro, Crivellaro, Sabrina, Panuzzo, Cristina, Carrà, Giovanna, Guerrasio, Angelo, Saglio, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351326/ https://www.ncbi.nlm.nih.gov/pubmed/28356925 http://dx.doi.org/10.3892/ol.2016.5465 |
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