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Reversibility of Apixaban Anticoagulation with a Four‐Factor Prothrombin Complex Concentrate in Healthy Volunteers

It was hypothesized that the four‐factor prothrombin complex concentrate (4F‐PCC) Kcentra 25 unit/kg would reverse impairment of thrombin generation in healthy volunteers dosed with apixaban to steady state. In this randomized, two‐period crossover, assessor‐blinded trial, 12 healthy subjects receiv...

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Detalles Bibliográficos
Autores principales:	Nagalla, S, Thomson, L, Oppong, Y, Bachman, B, Chervoneva, I, Kraft, WK
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351332/ https://www.ncbi.nlm.nih.gov/pubmed/27170068 http://dx.doi.org/10.1111/cts.12398

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