The Pharmacokinetic Exposure to Fexofenadine is Volume‐Dependently Reduced in Healthy Subjects Following Oral Administration With Apple Juice

Pharmacokinetic exposures to fexofenadine (FEX) are reduced by apple juice (AJ); however, the relationship between the AJ volume and the degree of AJ‐FEX interaction has not been understood. In this crossover study, 10 healthy subjects received single doses of FEX 60 mg with different volumes (150,...

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Detalles Bibliográficos
Autores principales: Luo, J, Imai, H, Ohyama, T, Hashimoto, S, Hasunuma, T, Inoue, Y, Kotegawa, T, Ohashi, K, Uemura, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351340/
https://www.ncbi.nlm.nih.gov/pubmed/27197662
http://dx.doi.org/10.1111/cts.12400

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