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Multicenter phase II study of infusional 5-fluorouracil (5-FU), leucovorin, and oxaliplatin, plus biweekly cetuximab as first-line treatment in patients with metastatic colorectal cancer (CELINE trial)

The current phase II study investigated the efficacy and safety of biweekly cetuximab combined with standard oxaliplatin-based chemotherapy [infusional 5-fluorouracil (5-FU), leucovorin, and oxaliplatin (FOLFOX-6)] in the first-line treatment of KRAS wild-type metastatic colorectal cancer (mCRC). Si...

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Detalles Bibliográficos
Autores principales: Kotake, Masanori, Aoyama, Toru, Munemoto, Yoshinori, Doden, Kenji, Kataoka, Masato, Kobayashi, Kenji, Nishimura, Genichi, Fujita, Hidehito, Nakamura, Keishi, Takehara, Akira, Tanaka, Chihiro, Sakamoto, Junichi, Nagata, Naoki, Oba, Koji, Kondo, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351391/
https://www.ncbi.nlm.nih.gov/pubmed/28356954
http://dx.doi.org/10.3892/ol.2016.5505