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Multicenter phase II study of infusional 5-fluorouracil (5-FU), leucovorin, and oxaliplatin, plus biweekly cetuximab as first-line treatment in patients with metastatic colorectal cancer (CELINE trial)
The current phase II study investigated the efficacy and safety of biweekly cetuximab combined with standard oxaliplatin-based chemotherapy [infusional 5-fluorouracil (5-FU), leucovorin, and oxaliplatin (FOLFOX-6)] in the first-line treatment of KRAS wild-type metastatic colorectal cancer (mCRC). Si...
Autores principales: | Kotake, Masanori, Aoyama, Toru, Munemoto, Yoshinori, Doden, Kenji, Kataoka, Masato, Kobayashi, Kenji, Nishimura, Genichi, Fujita, Hidehito, Nakamura, Keishi, Takehara, Akira, Tanaka, Chihiro, Sakamoto, Junichi, Nagata, Naoki, Oba, Koji, Kondo, Ken |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351391/ https://www.ncbi.nlm.nih.gov/pubmed/28356954 http://dx.doi.org/10.3892/ol.2016.5505 |
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